Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:10mg 68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCO)C(C)(C)C)C=C1 Purity (HPLC)

68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CP-DOTA is a SNAP-tag substrate containg the macrocyclic chelator DOTA moiety

Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide

1039/D4CB00184B

137 Purity (HPLC) >= 95% Solubility DMSO

Gly-Gly-Phe-Gly-PAB(m-PEG8) Size:10mg 68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCO)C(C)(C)C)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be