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The Mal-Propionyl group may also improve retro-Michael addition stability during antibody conjugation
Nature 588
486 Purity (HPLC) >= 95% Solubility DMSO
S)-AHPC-acetamido-O-PEG1-C2-amine HCl Synonyms CAS Number 2097973-72-1 Related CAS 2010159-60-9 (free base)
Binfunctional carboxylic acid-carboxylic acid linker
Mal-Lys(m-PEG4)-Val-Ala-PAB-PNP Size:50mg The Mal-Propionyl group may alsoSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine
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