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DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg 126 Purity (HPLC) >= 95%

SKU 82216988419
4.5
USD445.00 USD467.00

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Description

126 Purity (HPLC) >= 95% Solubility DMSO

75 SMILES Cl

The water-soluble PEG3 spacer should minimize the interaction between the dye and the biomolecule to be labeled

308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Pure 6-isomer

DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg 126 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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