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Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg BG- diAcFAM is a SNAP-tag

SKU 81606925103
4.8
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Description

BG- diAcFAM is a SNAP-tag substrate containg diAcFAM dye

The water soluble 5(6)-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group

eLife 2018

362 SMILES OCCCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-acetamido-O-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C36H56N4O11S Molecular Weight 752

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg BG- diAcFAM is a SNAP-tagSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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