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Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg Product Name DOTA-tris(t-Bu)ester-C2-acid Synonyms CAS

SKU 80648920072
4.5
EUR445.00 EUR481.00

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Description

Product Name DOTA-tris(t-Bu)ester-C2-acid Synonyms CAS Number n/a Related CAS Molecular Formula C31H57N5O9 Molecular Weight 643

When introduced to cells

Product Name: Cy3 azide trisulfo Synonyms: Cy3 azide

Product Name Thalidomide-C3-OH Synonyms Thalidomide-4'-C3-OH CAS Number 2357113-44-9 Related CAS Molecular Formula C16H16N2O5 Molecular Weight 316

References

Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg Product Name DOTA-tris(t-Bu)ester-C2-acid Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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