tert-butyl 4-[2-(2-aminoethoxy)ethyl]piperazine-1-carboxylate linker 559 SMILES OC(=O)CCOCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

559 SMILES OC(=O)CCOCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

nM for cereblon-binding affinity

68 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

234 SMILES BrCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl 2-(piperazin-1-yl)acetate Synonyms CAS Number 112257-22-4 Related CAS Molecular Formula C10H20N2O2 Molecular Weight 200

tert-butyl 4-[2-(2-aminoethoxy)ethyl]piperazine-1-carboxylate linker 559 SMILES OC(=O)CCOCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)Nitrogen Heterocycle Based Linker (NHBL). Binfunctional amine amine linker. Product Name tert butyl 4 [2 (2 aminoethoxy)ethyl]piperazine 1 carboxylate Synonyms CAS Number 1181972 47 3 Related CAS Molecular Formula C13H27N3O3 Molecular Weight 273. 377 SMILES CC(C)(C)OC(=O)N1CCN(CCOCCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For