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MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg Fluorescein dye (494Ex/526Em) is one

SKU 69617705082
4.8
USD495.00 USD527.00

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Ships within 48 hours · Estimated delivery Aug 17 - Aug 22

Description

Fluorescein dye (494Ex/526Em) is one of the most popular green fluorescent reagents used for in situ labeling of peptides

Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C63H91N9O17 Molecular Weight 1246

NRX-103095 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

362 SMILES OCCCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

09 Purity (HPLC) >= 95% Solubility DMSO

MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg Fluorescein dye (494Ex/526Em) is oneSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker

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