Azide-Dap(m-PEG4)-Val-Ala-PAB Size:25mg 98 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCN3C(=O)C=CC3=O)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)N(CCCS([O-])(=O)=O)C2=CC=C(C=C12)S(O)(=O)=O Purity (HPLC):

98 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCN3C(=O)C=CC3=O)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)N(CCCS([O-])(=O)=O)C2=CC=C(C=C12)S(O)(=O)=O Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

85 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

also referred to as the Cu(I)-catalyzed free click reaction

Swierczynska

36 Purity (HPLC) >= 95% Solubility DMSO

Azide-Dap(m-PEG4)-Val-Ala-PAB Size:25mg 98 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCN3C(=O)C=CC3=O)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)N(CCCS([O-])(=O)=O)C2=CC=C(C=C12)S(O)(=O)=O Purity (HPLC):SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine