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Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C110H170N14O30 Molecular Weight 2168
611 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Journal of Medicinal Chemistry 2021
It has the spectral properties identical to those of TRITC conjugates
146 SMILES BrC1=CC=C2CN(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP peg Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or
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