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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg Product Name DOTA-C5-alcohol Synonyms CAS

SKU 2022111908
4.2
USD495.00 USD529.00

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Description

Product Name DOTA-C5-alcohol Synonyms CAS Number n/a Related CAS Molecular Formula C21H39N5O8 Molecular Weight 489

28 Purity (HPLC) >= 95% Solubility DMSO

11 Purity (HPLC) >= 95% Solubility DMSO

69 SMILES Cl

Product Name Thalidomide-O-PEG5-C2-acid Synonyms Thalidomide-4'-O-PEG5-C2-acid CAS Number 2353563-48-9 Related CAS Molecular Formula C26H34N2O12 Molecular Weight 566

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg Product Name DOTA-C5-alcohol Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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