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Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr emission maximum = 660 nm

SKU 12194433127
4.6
EUR445.00 EUR470.00

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Description

emission maximum = 660 nm

Product Name tert-butyl 2-[4-(piperidin-4-yl)piperazin-1-yl]acetate Synonyms CAS Number 688020-38-4 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

Product Name NDB-TM Synonyms CAS Number 871510-38-2 Related CAS Molecular Formula C10H10N4O3S Molecular Weight 266

Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C43H68N6O16 Molecular Weight 925

Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr emission maximum = 660 nmSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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